Fwd: PNAS Early Edition for 25 Jun 2015

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Proceedings of the National Academy of Sciences Early Edition articles for 25 June 2015 Letters (Online Only) Metaanalysis of flawed expression profiling data leading to erroneous Parkinson's biomarker identification Lilah Toker and Paul Pavlidis Reply to Toker and Pavlidis: Blood biomarkers for Parkinson's disease Jose A. Santiago and Judith A. Potashkin QnAs QnAs with James J. Collins Tinsley H. Davis Commentaries Less than the sum of its parts, a leinamycin precursor has superior properties William P. Katt and Richard A. Cerione Ocean stoichiometry, global carbon, and climate Robert W. Sterner Physical Sciences Applied Physical Sciences Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors Francois Bordeleau, Joseph P. Califano, Yashira L. Negrón Abril, Brooke N. Mason, Danielle J. LaValley, Sandra J. Shin, Robert S. Weiss, and Cynthia A. Reinhart-King Pathways to dewetting in hydrophobic confinement Richard C. Remsing, Erte Xi, Srivathsan Vembanur, Sumit Sharma, Pablo G. Debenedetti, Shekhar Garde, and Amish J. Patel Chemistry Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB1 Jonathan F. Fay and David L. Farrens Self-reproducing catalyst drives repeated phospholipid synthesis and membrane growth Michael D. Hardy, Jun Yang, Jangir Selimkhanov, Christian M. Cole, Lev S. Tsimring, and Neal K. Devaraj Structural insights into the recognition of cisplatin and AAF-dG lesion by Rad14 (XPA) Sandra C. Koch, Jochen Kuper, Karola L. Gasteiger, Nina Simon, Ralf Strasser, David Eisen, Simon Geiger, Sabine Schneider, Caroline Kisker, and Thomas Carell Earth, Atmospheric, and Planetary Sciences Biologically recycled continental iron is a major component in banded iron formations Weiqiang Li, Brian L. Beard, and Clark M. Johnson Physics Cooperative strings and glassy interfaces Thomas Salez, Justin Salez, Kari Dalnoki-Veress, Elie Raphaël, and James A. Forrest Solid−liquid critical behavior of water in nanopores Kenji Mochizuki and Kenichiro Koga Relationship between thermoelectric figure of merit and energy conversion efficiency Hee Seok Kim, Weishu Liu, Gang Chen, Ching-Wu Chu, and Zhifeng Ren Effect of salt on the H-bond symmetrization in ice  Livia Eleonora Bove, Richard Gaal, Zamaan Raza, Adriaan-Alexander Ludl, Stefan Klotz, Antonino Marco Saitta, Alexander F. Goncharov, and Philippe Gillet Developed turbulence and nonlinear amplification of magnetic fields in laboratory and astrophysical plasmas Jena Meinecke, Petros Tzeferacos, Anthony Bell, Robert Bingham, Robert Clarke, Eugene Churazov, Robert Crowston, Hugo Doyle, R. Paul Drake, Robert Heathcote, Michel Koenig, Yasuhiro Kuramitsu, Carolyn Kuranz, Dongwook Lee, Michael MacDonald, Christopher Murphy, Margaret Notley, Hye-Sook Park, Alexander Pelka, Alessandra Ravasio, Brian Reville, Youichi Sakawa, Willow Wan, Nigel Woolsey, Roman Yurchak, Francesco Miniati, Alexander Schekochihin, Don Lamb, and Gianluca Gregori Social Sciences Anthropology Human population dynamics in Europe over the Last Glacial Maximum Miikka Tallavaara, Miska Luoto, Natalia Korhonen, Heikki Järvinen, and Heikki Seppä Early procurement of scarlet macaws and the emergence of social complexity in Chaco Canyon, NM  Adam S. Watson, Stephen Plog, Brendan J. Culleton, Patricia A. Gilman, Steven A. LeBlanc, Peter M. Whiteley, Santiago Claramunt, and Douglas J. Kennett Psychological and Cognitive Sciences Top-down control of the phase of alpha-band oscillations as a mechanism for temporal prediction Jason Samaha, Phoebe Bauer, Sawyer Cimaroli, and Bradley R. Postle Adolescent impatience decreases with increased frontostriatal connectivity Wouter van den Bos, Christian A. Rodriguez, Julie B. Schweitzer, and Samuel M. McClure The self-control consequences of political ideology Joshua J. Clarkson, John R. Chambers, Edward R. Hirt, Ashley S. Otto, Frank R. Kardes, and Christopher Leone Individual olfactory perception reveals meaningful nonolfactory genetic information  Lavi Secundo, Kobi Snitz, Kineret Weissler, Liron Pinchover, Yehuda Shoenfeld, Ron Loewenthal, Nancy Agmon-Levin, Idan Frumin, Dana Bar-Zvi, Sagit Shushan, and Noam Sobel Biological Sciences Anthropology Human population dynamics in Europe over the Last Glacial Maximum Miikka Tallavaara, Miska Luoto, Natalia Korhonen, Heikki Järvinen, and Heikki Seppä Applied Biological Sciences Engineering Escherichia coli coculture systems for the production of biochemical products  Haoran Zhang, Brian Pereira, Zhengjun Li, and Gregory Stephanopoulos Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery Jicheng Yu, Yuqi Zhang, Yanqi Ye, Rocco DiSanto, Wujin Sun, Davis Ranson, Frances S. Ligler, John B. Buse, and Zhen Gu Biochemistry A retro-biosynthetic approach to the prediction of biosynthetic pathways from position-specific isotope analysis as shown for tramadol Katarzyna M. Romek, Pierrick Nun, Gérald S. Remaud, Virginie Silvestre, Germain Sotoing Taïwe, Florine Lecerf-Schmidt, Ahcène Boumendjel, Michel De Waard, and Richard J. Robins DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity Mónica Berjón-Otero, Laurentino Villar, Miguel de Vega, Margarita Salas, and Modesto Redrejo-Rodríguez Generating new prions by targeted mutation or segment duplication Kacy R. Paul, Connor G. Hendrich, Aubrey Waechter, Madison R. Harman, and Eric D. Ross Structural insights into the recognition of cisplatin and AAF-dG lesion by Rad14 (XPA) Sandra C. Koch, Jochen Kuper, Karola L. Gasteiger, Nina Simon, Ralf Strasser, David Eisen, Simon Geiger, Sabine Schneider, Caroline Kisker, and Thomas Carell An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α Margarito Rojas, Gabriel Vasconcelos, and Thomas E. Dever Structural and functional insights into Escherichia coli α2-macroglobulin endopeptidase snap-trap inhibition Irene Garcia-Ferrer, Pedro Arêde, Josué Gómez-Blanco, Daniel Luque, Stephane Duquerroy, José R. Castón, Theodoros Goulas, and F. Xavier Gomis-Rüth Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan Longyan Zhao, Mingyi Wu, Chuang Xiao, Lian Yang, Lutan Zhou, Na Gao, Zi Li, Jun Chen, Jianchao Chen, Jikai Liu, Hongbo Qin, and Jinhua Zhao Biophysics and Computational Biology Protein misfolding occurs by slow diffusion across multiple barriers in a rough energy landscape Hao Yu, Derek R. Dee, Xia Liu, Angela M. Brigley, Iveta Sosova, and Michael T. Woodside Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics Joseph A. Liberman, Krishna C. Suddala, Asaminew Aytenfisu, Dalen Chan, Ivan A. Belashov, Mohammad Salim, David H. Mathews, Robert C. Spitale, Nils G. Walter, and Joseph E. Wedekind Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similar Michael C. Baxa, Wookyung Yu, Aashish N. Adhikari, Liang Ge, Zhen Xia, Ruhong Zhou, Karl F. Freed, and Tobin R. Sosnick Antibiotic efficacy is linked to bacterial cellular respiration   Michael A. Lobritz, Peter Belenky, Caroline B. M. Porter, Arnaud Gutierrez, Jason H. Yang, Eric G. Schwarz, Daniel J. Dwyer, Ahmad S. Khalil, and James J. Collins Cell Biology The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation Chiara Pastori, Philipp Kapranov, Clara Penas, Veronica Peschansky, Claude-Henry Volmar, Jann N. Sarkaria, Amade Bregy, Ricardo Komotar, Georges St. Laurent, Nagi G. Ayad, and Claes Wahlestedt Vimentin filament precursors exchange subunits in an ATP-dependent manner Amélie Robert, Molly J. Rossow, Caroline Hookway, Stephen A. Adam, and Vladimir I. Gelfand Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling Charles W. Morgan, Juan E. Diaz, Samantha G. Zeitlin, Daniel C. Gray, and James A. Wells Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors Francois Bordeleau, Joseph P. Califano, Yashira L. Negrón Abril, Brooke N. Mason, Danielle J. LaValley, Sandra J. Shin, Robert S. Weiss, and Cynthia A. Reinhart-King BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase Abid Khan, Sumanprava Giri, Yating Wang, Arindam Chakraborty, Archit K. Ghosh, Aparna Anantharaman, Vasudha Aggarwal, Kizhakke M. Sathyan, Taekjip Ha, Kannanganattu V. Prasanth, and Supriya G. Prasanth Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1 Ljiljana Milenkovic, Lucien E. Weiss, Joshua Yoon, Theodore L. Roth, YouRong S. Su, Steffen J. Sahl, Matthew P. Scott, and W. E. Moerner Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c  Shun-ichiro Asahara, Hiroaki Etoh, Hiroyuki Inoue, Kyoko Teruyama, Yuki Shibutani, Yuka Ihara, Yukina Kawada, Alberto Bartolome, Naoko Hashimoto, Tomokazu Matsuda, Maki Koyanagi-Kimura, Ayumi Kanno, Yushi Hirota, Tetsuya Hosooka, Kazuaki Nagashima, Wataru Nishimura, Hiroshi Inoue, Michihiro Matsumoto, Michael J. Higgins, Kazuki Yasuda, Nobuya Inagaki, Susumu Seino, Masato Kasuga, and Yoshiaki Kido DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination  Leizhen Wei, Satoshi Nakajima, Stefanie Böhm, Kara A. Bernstein, Zhiyuan Shen, Michael Tsang, Arthur S. Levine, and Li Lan Ecology Backbones of evolutionary history test biodiversity theory for microbes  James P. O'Dwyer, Steven W. Kembel, and Thomas J. Sharpton Assessing niche width of endothermic fish from genes to ecosystem Daniel J. Madigan, Aaron B. Carlisle, Luke D. Gardner, Nishad Jayasundara, Fiorenza Micheli, Kurt M. Schaefer, Daniel W. Fuller, and Barbara A. Block Climate-driven diversity loss in a grassland community Susan P. Harrison, Elise S. Gornish, and Stella Copeland Evolution The butterfly plant arms-race escalated by gene and genome duplications  Patrick P. Edger, Hanna M. Heidel-Fischer, Michaël Bekaert, Jadranka Rota, Gernot Glöckner, Adrian E. Platts, David G. Heckel, Joshua P. Der, Eric K. Wafula, Michelle Tang, Johannes A. Hofberger, Ann Smithson, Jocelyn C. Hall, Matthieu Blanchette, Thomas E. Bureau, Stephen I. Wright, Claude W. dePamphilis, M. Eric Schranz, Michael S. Barker, Gavin C. Conant, Niklas Wahlberg, Heiko Vogel, J. Chris Pires, and Christopher W. Wheat Miniaturized mitogenome of the parasitic plant Viscum scurruloideum is extremely divergent and dynamic and has lost all nad genes Elizabeth Skippington, Todd J. Barkman, Danny W. Rice, and Jeffrey D. Palmer Swimming muscles power suction feeding in largemouth bass Ariel L. Camp, Thomas J. Roberts, and Elizabeth L. Brainerd Genetics Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior  John Shorter, Charlene Couch, Wen Huang, Mary Anna Carbone, Jason Peiffer, Robert R. H. Anholt, and Trudy F. C. Mackay Environmental CO2 inhibits Caenorhabditis elegans egg-laying by modulating olfactory neurons and evokes widespread changes in neural activity  Lorenz A. Fenk and Mario de Bono Genetic and epigenetic architecture of sex-biased expression in the jewel wasps Nasonia vitripennis and giraulti Xu Wang, John H. Werren, and Andrew G. Clark The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes Patrick L. Collins, Katherine E. Kyle, Takeshi Egawa, Yoichi Shinkai, and Eugene M. Oltz Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation  Kelan Chen, Jiang Hu, Darcy L. Moore, Ruijie Liu, Sarah A. Kessans, Kelsey Breslin, Isabelle S. Lucet, Andrew Keniry, Huei San Leong, Clare L. Parish, Douglas J. Hilton, Richard J. L. F. Lemmers, Silvère M. van der Maarel, Peter E. Czabotar, Renwick C. J. Dobson, Matthew E. Ritchie, Graham F. Kay, James M. Murphy, and Marnie E. Blewitt Immunology and Inflammation Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA Anne-Claire Duchez, Luc H. Boudreau, James Bollinger, Clémence Belleannée, Nathalie Cloutier, Benoit Laffont, Raifish E. Mendoza-Villarroel, Tania Lévesque, Emmanuelle Rollet-Labelle, Matthieu Rousseau, Isabelle Allaeys, Jacques J. Tremblay, Patrice E. Poubelle, Gérard Lambeau, Marc Pouliot, Patrick Provost, Denis Soulet, Michael H. Gelb, and Eric Boilard CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance Rajesh Rajaiah, Darren J. Perkins, Derek D. C. Ireland, and Stefanie N. Vogel DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice Nehemiah Cox, Darrell Pilling, and Richard H. Gomer Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial  Peter J. Kuebler, Megha L. Mehrotra, J. Jeff McConnell, Sara J. Holditch, Brian I. Shaw, Leandro F. Tarosso, Kaitlyn S. Leadabrand, Jeffrey M. Milush, Vanessa A. York, Rui André Saraiva Raposo, Rex G. Cheng, Emily M. Eriksson, Vanessa McMahan, David V. Glidden, Stephen Shiboski, Robert M. Grant, Douglas F. Nixon, and Esper G. Kallás Medical Sciences Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice Luca Bravi, Noemi Rudini, Roberto Cuttano, Costanza Giampietro, Luigi Maddaluno, Luca Ferrarini, Ralf H. Adams, Monica Corada, Gwenola Boulday, Elizabeth Tournier-Lasserve, Elisabetta Dejana, and Maria Grazia Lampugnani Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization  Peter Charbel Issa, Alun R. Barnard, Philipp Herrmann, Ilyas Washington, and Robert E. MacLaren Disruption of prostaglandin E2 receptor EP4 impairs urinary concentration via decreasing aquaporin 2 in renal collecting ducts Min Gao, Rong Cao, Shengnan Du, Xiao Jia, Senfeng Zheng, Shizheng Huang, Qifei Han, Jia Liu, Xiaoyan Zhang, Yifei Miao, Jihong Kang, Jan-Åke Gustafsson, and Youfei Guan Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer Linda Henneman, Martine H. van Miltenburg, Ewa M. Michalak, Tanya M. Braumuller, Janneke E. Jaspers, Anne Paulien Drenth, Renske de Korte-Grimmerink, Ewa Gogola, Karoly Szuhai, Andreas Schlicker, Rahmen Bin Ali, Colin Pritchard, Ivo J. Huijbers, Anton Berns, Sven Rottenberg, and Jos Jonkers Microbiology Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health  Kathryn E. Holt, Heiman Wertheim, Ruth N. Zadoks, Stephen Baker, Chris A. Whitehouse, David Dance, Adam Jenney, Thomas R. Connor, Li Yang Hsu, Juliëtte Severin, Sylvain Brisse, Hanwei Cao, Jonathan Wilksch, Claire Gorrie, Mark B. Schultz, David J. Edwards, Kinh Van Nguyen, Trung Vu Nguyen, Trinh Tuyet Dao, Martijn Mensink, Vien Le Minh, Nguyen Thi Khanh Nhu, Constance Schultsz, Kuntaman Kuntaman, Paul N. Newton, Catrin E. Moore, Richard A. Strugnell, and Nicholas R. Thomson A self-lysis pathway that enhances the virulence of a pathogenic bacterium Kirsty A. McFarland, Emily L. Dolben, Michele LeRoux, Tracy K. Kambara, Kathryn M. Ramsey, Robin L. Kirkpatrick, Joseph D. Mougous, Deborah A. Hogan, and Simon L. Dove Neuroscience Activity-dependent synaptic GRIP1 accumulation drives synaptic scaling up in response to action potential blockade Melanie A. Gainey, Vedakumar Tatavarty, Marc Nahmani, Heather Lin, and Gina G. Turrigiano Ongoing dynamics in large-scale functional connectivity predict perception Sepideh Sadaghiani, Jean-Baptiste Poline, Andreas Kleinschmidt, and Mark D'Esposito Top-down control of the phase of alpha-band oscillations as a mechanism for temporal prediction Jason Samaha, Phoebe Bauer, Sawyer Cimaroli, and Bradley R. Postle RNA ligation in neurons by RtcB inhibits axon regeneration Sara Guckian Kosmaczewski, Sung Min Han, Bingjie Han, Benjamin Irving Meyer, Huma S. Baig, Wardah Athar, Alexander T. Lin-Moore, Michael R. Koelle, and Marc Hammarlund Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex Ali Shahmoradi, Konstantin Radyushkin, and Moritz J. Rossner Theta–gamma coordination between anterior cingulate and prefrontal cortex indexes correct attention shifts Benjamin Voloh, Taufik A. Valiante, Stefan Everling, and Thilo Womelsdorf Individual olfactory perception reveals meaningful nonolfactory genetic information  Lavi Secundo, Kobi Snitz, Kineret Weissler, Liron Pinchover, Yehuda Shoenfeld, Ron Loewenthal, Nancy Agmon-Levin, Idan Frumin, Dana Bar-Zvi, Sagit Shushan, and Noam Sobel Pharmacology Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB1 Jonathan F. Fay and David L. Farrens A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels  Luisa Maria Rosaria Napolitano, Ina Bisha, Matteo De March, Arin Marchesi, Manuel Arcangeletti, Nicola Demitri, Monica Mazzolini, Alex Rodriguez, Alessandra Magistrato, Silvia Onesti, Alessandro Laio, and Vincent Torre Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer Jordi Bonaventura, Gemma Navarro, Verònica Casadó-Anguera, Karima Azdad, William Rea, Estefanía Moreno, Marc Brugarolas, Josefa Mallol, Enric I. Canela, Carme Lluís, Antoni Cortés, Nora D. Volkow, Serge N. Schiffmann, Sergi Ferré, and Vicent Casadó N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias Antonio G. Soto, Thomas H. Smith, Buxin Chen, Supriyo Bhattacharya, Isabel Canto Cordova, Terry Kenakin, Nagarajan Vaidehi, and JoAnn Trejo Plant Biology Phosphorylation is an on/off switch for 5-hydroxyconiferaldehyde O-methyltransferase activity in poplar monolignol biosynthesis Jack P. Wang, Ling Chuang, Philip L. Loziuk, Hao Chen, Ying-Chung Lin, Rui Shi, Guan-Zheng Qu, David C. Muddiman, Ronald R. Sederoff, and Vincent L. Chiang Trp triad-dependent rapid photoreduction is not required for the function of Arabidopsis CRY1 Jie Gao, Xu Wang, Meng Zhang, Mingdi Bian, Weixian Deng, Zecheng Zuo, Zhenming Yang, Dongping Zhong, and Chentao Lin Osmotic stress induces phosphorylation of histone H3 at threonine 3 in pericentromeric regions of Arabidopsis thaliana Zhen Wang, Juan Armando Casas-Mollano, Jianping Xu, Jean-Jack M. Riethoven, Chi Zhang, and Heriberto Cerutti Psychological and Cognitive Sciences Adolescent impatience decreases with increased frontostriatal connectivity Wouter van den Bos, Christian A. Rodriguez, Julie B. Schweitzer, and Samuel M. McClure Systems Biology Synaptic clusters function as odor operators in the olfactory bulb Michele Migliore, Francesco Cavarretta, Addolorata Marasco, Eleonora Tulumello, Michael L. Hines, and Gordon M. Shepherd Integrated, systems metabolic picture of acetone-butanol-ethanol fermentation by Clostridium acetobutylicum Chen Liao, Seung-Oh Seo, Venhar Celik, Huaiwei Liu, Wentao Kong, Yi Wang, Hans Blaschek, Yong-Su Jin, and Ting Lu Corrections Correction for Thompson et al., Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye Correction for Bartolomé et al., Hydrological change in Southern Europe responding to increasing North Atlantic overturning during Greenland Stadial 1 Correction for Balakrishnan et al., Novel pathways for fuels and lubricants from biomass optimized using life-cycle greenhouse gas assessment Correction for Gursoy-Yuzugullu et al., Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair SI Correction Correction to Supporting Information for Sullivan et al., Spatially robust estimates of biological nitrogen (N) fixation imply substantial human alteration of the tropical N cycle Correction to Supporting Information for Talantova et al., Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss Open Access From the Cover Inaugural Article Classic Cozzarelli Prize Winner Front Matter This message was sent to pascal.alter@gmail.com. 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