---------- Forwarded message ----------
From: Newsletter Phys.org <not-for-reply@physorg.com>
Date: Mon, Dec 9, 2013 at 1:40 AM
Subject: Phys.org Newsletter Sunday, Dec 8
To: Pascal Alter <pascal.alter@gmail.com>
From: Newsletter Phys.org <not-for-reply@physorg.com>
Date: Mon, Dec 9, 2013 at 1:40 AM
Subject: Phys.org Newsletter Sunday, Dec 8
To: Pascal Alter <pascal.alter@gmail.com>
Dear Pascal Alter,
Here is your customized Phys.org Newsletter for December 8, 2013:
- Gene CUX1 discovered to play part in one per cent of all cancers
- Electrical control of single atom magnets
- Who's patenting whose genome?
- Surprising diversity in aging revealed in nature
- Extensive variability in olfactory receptors influences human odor perception
- Blunting brain tumor growth with immune activation
- New formula for fast, abundant hydrogen production may help power fuel cells
- Flipping a gene switch reactivates fetal hemoglobin, may reverse sickle cell disease
- Saudi, China scientists decode date-palm tree DNA
- Peculiar traffic routes suggest hijacking headaches
- New consoles, online games to keep market soaring to 2017
- Gene therapy scores big wins against blood cancers
- Experts urge US to measure, pursue our happiness
- Apple wants Samsung to pay $22M for legal bills
Hong Kong on Saturday quarantined an additional 19 people after the city confirmed its second human case of the deadly H7N9 bird flu, less than five days after it confirmed its first, officials said.
Calif. health exchange shares data without consent
The California health exchange is giving the names of tens of thousands of consumers to insurance agents without their knowledge.
New insights into pathophysiology of sickle cell disease and thalassemia may help improve care
New research presented today during the 55th American Society of Hematology Annual Meeting and Exposition in New Orleans uncovers several important insights into the pathophysiology of sickle cell disease and thalassemia that may soon translate into the development of better, more targeted treatments for hundreds of thousands of patients worldwide.
Economic factors may affect getting guideline-recommended breast cancer treatment
Women with interruptions in health insurance coverage or with low income levels had a significantly increased likelihood of failing to receive breast cancer care that is in concordance with recommended treatment guidelines, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Diabetes identified as risk factor for liver cancer across ethnic groups
Diabetes was associated with an increased risk for developing a type of liver cancer called hepatocellular carcinoma, and this association was highest for Latinos, followed by Hawaiians, African-Americans, and Japanese-Americans, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Hong Kong reports 2nd H7N9 bird flu case
Hong Kong reported its second human case of H7N9 bird flu just days after the first, raising fears that the virus is spreading beyond mainland China.
Survey: Knowledge about HPV vaccine effectiveness lacking
Knowledge about the efficacy of the human papillomavirus (HPV) vaccine in preventing cervical cancer was lacking in the majority of survey respondents for whom the information would be relevant, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
International gene therapy trial for 'bubble boy' disease shows promising early results
Hematopoietic stem cell transplantation (HSCT), once considered an effective yet risky alternative to drug therapy for blood cancer, has become more accessible and successful in a wide range of patients as a result of major advances in transplant strategies and technologies. Several studies representing these advances were presented today during the 55th American Society of Hematology Annual Meeting and Exposition in New Orleans.
Genetic mutations and molecular alterations may explain racial differences in head and neck cancers
A team of scientists at Johns Hopkins and in Texas has identified a handful of genetic mutations in black Americans, in addition to some chemical alterations affecting gene activity, which may help explain why the death rate among African-Americans from the most common form of head and neck cancer continues to hover some 18 percent higher above the death rate of whites with the same cancer.
High-tech gene-therapy advances offer hope for patients with hard-to-treat blood disorders
A series of advancements in genetically engineered cell therapies demonstrate early efficacy and safety in patients with blood disorders for whom standard treatments have been unsuccessful, according to data showcased today during the 55th American Society of Hematology (ASH) Annual Meeting and Exposition in New Orleans.
T cell immunotherapy: Promising results in children and adults with leukemia
Nearly 90 percent of children and adults with a highly aggressive form of acute lymphoblastic leukemia (ALL) showed no evidence of cancer after receiving a novel, personalized cell therapy that reprograms a patient's immune system. In pilot studies of bioengineered T cells that attack leukemia, 24 of 27 patients (89%) experienced complete responses within 28 days after treatment. In all, 27 patients received the treatment—22 children treated at The Children's Hospital of Philadelphia and five adults treated at the Hospital of the University of Pennsylvania.
Rare cause of anemia in newborns often overlooked, research suggests
Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment, say scientists from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.
Age shouldn't limit access to transplants for MDS, study suggests
Patients with myelodysplastic syndromes (MDS) who were as old as 74 fared as well with stem cell transplantation as did patients in the 60-to-65 age range, according to a study from Dana-Farber Cancer Institute presented at the annual meeting of the American Society of Hematology.
Majority of epilepsy surgery patients enjoy improvement in their physical and social well-being
The majority of epilepsy patients who have brain surgery to treat their disorder are satisfied with the results in reducing epilepsy-related seizures and improving their psychological and social well-being.
Targeted treatment can significantly reduce relapse in children with AML leukemia
The addition of a monoclonal antibody called gemtuzumab combined with standard chemotherapy has been shown to significantly reduce the risk of relapse and increase rates of disease-free survival in pediatric patients with acute myeloid leukemia (AML). Post-treatment relapse rates are a major indicator of potential for long-term survival in children with the disease.
Novel drug regimen can improve stem cell transplantation outcomes
Adding bortezomib (Velcade) to standard preventive therapy for graft-versus-host-disease (GVHD) results in improved outcomes for patients receiving stem-cell transplants from mismatched and unrelated donors, according to researchers from Dana-Farber Cancer Institute.
Potential biological factor contributing to racial disparities in prostate cancer
Researchers have uncovered a potential biological factor that may contribute to disparities in prostate cancer incidence and mortality between African-American and non-Hispanic white men in the United States, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Biomarker linked to aggressive breast cancers, poor outcomes in African-Americans
Among African-American women with breast cancer, increased levels of the protein HSET were associated with worse breast cancer outcomes, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Medical students find mind-body regulation training helpful
(HealthDay)—A practical approach may be used to offer mind-body regulation training to medical students, according to research published in the Fall issue of the Annals of Behavioral Science and Medical Education.
Nerve root sedimentation sign for spinal stenosis assessed
(HealthDay)—The nerve root sedimentation sign (SedSign), seen on magnetic resonance images, can differentiate lumbar spinal stenosis (LSS) from asymptomatic controls, according to a study published in the Nov. 15 issue of Spine.
Pre-op MRI of margins predicts rectal cancer outcomes
(HealthDay)—Preoperative high-resolution magnetic resonance imaging (MRI) assessment of circumferential resection margin (CRM) status predicts survival and other disease progression outcomes in patients with rectal cancer, according to a study published online Nov. 25 in the Journal of Clinical Oncology.
Experts urge US to measure, pursue our happiness
A panel of experts thinks the U.S. government should be more in touch with Americans' feelings.
Gene therapy scores big wins against blood cancers
In one of the biggest advances against leukemia and other blood cancers in many years, doctors are reporting unprecedented success by using gene therapy to transform patients' blood cells into soldiers that seek and destroy cancer.
Novel method could help bring cancer biomarkers to clinic
An international team of scientists led by Fred Hutchinson Cancer Research Center cancer proteomics expert Amanda Paulovich, M.D., has demonstrated the feasibility of large-scale, standardized protein measurements, which are necessary for validation of disease biomarkers and drug targets.
Extensive variability in olfactory receptors influences human odor perception
According to Gertrude Stein, "A rose is a rose is a rose," but new research indicates that might not be the case when it comes to the rose's scent. Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals. This substantial variation is in turn reflected by variability in how each person perceives odors.
Blunting brain tumor growth with immune activation
Researchers at the University of Calgary's Hotchkiss Brain Institute (HBI) have made a discovery that could lead to better treatment for patients suffering from brain cancer.
Flipping a gene switch reactivates fetal hemoglobin, may reverse sickle cell disease
Hematology researchers at The Children's Hospital of Philadelphia have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period. Because this fetal hemoglobin is unaffected by the genetic defect in sickle cell disease (SCD), the cell culture findings may open the door to a new therapy for the debilitating blood disorder.
Gene CUX1 discovered to play part in one per cent of all cancers
Researchers have identified a gene that drives the development of tumours in over one per cent of all cancer patients. This is the first time that the gene CUX1 has been broadly linked to cancer development.
Researchers film early concussion damage, describe brain's response to injury (w/ Video)
There is more than meets the eye following even a mild traumatic brain injury. While the brain may appear to be intact, new findings reported in Nature suggest that the brain's protective coverings may feel the brunt of the impact.
This email is a free service of Phys.org
You received this email because you subscribed to our list.
You are subscribed as pascal.alter@gmail.com
Here is your customized Phys.org Newsletter for December 8, 2013:
Spotlight Stories Headlines
- Researchers film early concussion damage, describe brain's response to injury (w/ Video)- Gene CUX1 discovered to play part in one per cent of all cancers
- Electrical control of single atom magnets
- Who's patenting whose genome?
- Surprising diversity in aging revealed in nature
- Extensive variability in olfactory receptors influences human odor perception
- Blunting brain tumor growth with immune activation
- New formula for fast, abundant hydrogen production may help power fuel cells
- Flipping a gene switch reactivates fetal hemoglobin, may reverse sickle cell disease
- Saudi, China scientists decode date-palm tree DNA
- Peculiar traffic routes suggest hijacking headaches
- New consoles, online games to keep market soaring to 2017
- Gene therapy scores big wins against blood cancers
- Experts urge US to measure, pursue our happiness
- Apple wants Samsung to pay $22M for legal bills
Medicine & Health news
Hong Kong quarantines 19 people over second bird flu caseHong Kong on Saturday quarantined an additional 19 people after the city confirmed its second human case of the deadly H7N9 bird flu, less than five days after it confirmed its first, officials said.
Calif. health exchange shares data without consent
The California health exchange is giving the names of tens of thousands of consumers to insurance agents without their knowledge.
New insights into pathophysiology of sickle cell disease and thalassemia may help improve care
New research presented today during the 55th American Society of Hematology Annual Meeting and Exposition in New Orleans uncovers several important insights into the pathophysiology of sickle cell disease and thalassemia that may soon translate into the development of better, more targeted treatments for hundreds of thousands of patients worldwide.
Economic factors may affect getting guideline-recommended breast cancer treatment
Women with interruptions in health insurance coverage or with low income levels had a significantly increased likelihood of failing to receive breast cancer care that is in concordance with recommended treatment guidelines, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Diabetes identified as risk factor for liver cancer across ethnic groups
Diabetes was associated with an increased risk for developing a type of liver cancer called hepatocellular carcinoma, and this association was highest for Latinos, followed by Hawaiians, African-Americans, and Japanese-Americans, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Hong Kong reports 2nd H7N9 bird flu case
Hong Kong reported its second human case of H7N9 bird flu just days after the first, raising fears that the virus is spreading beyond mainland China.
Survey: Knowledge about HPV vaccine effectiveness lacking
Knowledge about the efficacy of the human papillomavirus (HPV) vaccine in preventing cervical cancer was lacking in the majority of survey respondents for whom the information would be relevant, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
International gene therapy trial for 'bubble boy' disease shows promising early results
Hematopoietic stem cell transplantation (HSCT), once considered an effective yet risky alternative to drug therapy for blood cancer, has become more accessible and successful in a wide range of patients as a result of major advances in transplant strategies and technologies. Several studies representing these advances were presented today during the 55th American Society of Hematology Annual Meeting and Exposition in New Orleans.
Genetic mutations and molecular alterations may explain racial differences in head and neck cancers
A team of scientists at Johns Hopkins and in Texas has identified a handful of genetic mutations in black Americans, in addition to some chemical alterations affecting gene activity, which may help explain why the death rate among African-Americans from the most common form of head and neck cancer continues to hover some 18 percent higher above the death rate of whites with the same cancer.
High-tech gene-therapy advances offer hope for patients with hard-to-treat blood disorders
A series of advancements in genetically engineered cell therapies demonstrate early efficacy and safety in patients with blood disorders for whom standard treatments have been unsuccessful, according to data showcased today during the 55th American Society of Hematology (ASH) Annual Meeting and Exposition in New Orleans.
T cell immunotherapy: Promising results in children and adults with leukemia
Nearly 90 percent of children and adults with a highly aggressive form of acute lymphoblastic leukemia (ALL) showed no evidence of cancer after receiving a novel, personalized cell therapy that reprograms a patient's immune system. In pilot studies of bioengineered T cells that attack leukemia, 24 of 27 patients (89%) experienced complete responses within 28 days after treatment. In all, 27 patients received the treatment—22 children treated at The Children's Hospital of Philadelphia and five adults treated at the Hospital of the University of Pennsylvania.
Rare cause of anemia in newborns often overlooked, research suggests
Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment, say scientists from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.
Age shouldn't limit access to transplants for MDS, study suggests
Patients with myelodysplastic syndromes (MDS) who were as old as 74 fared as well with stem cell transplantation as did patients in the 60-to-65 age range, according to a study from Dana-Farber Cancer Institute presented at the annual meeting of the American Society of Hematology.
Majority of epilepsy surgery patients enjoy improvement in their physical and social well-being
The majority of epilepsy patients who have brain surgery to treat their disorder are satisfied with the results in reducing epilepsy-related seizures and improving their psychological and social well-being.
Targeted treatment can significantly reduce relapse in children with AML leukemia
The addition of a monoclonal antibody called gemtuzumab combined with standard chemotherapy has been shown to significantly reduce the risk of relapse and increase rates of disease-free survival in pediatric patients with acute myeloid leukemia (AML). Post-treatment relapse rates are a major indicator of potential for long-term survival in children with the disease.
Novel drug regimen can improve stem cell transplantation outcomes
Adding bortezomib (Velcade) to standard preventive therapy for graft-versus-host-disease (GVHD) results in improved outcomes for patients receiving stem-cell transplants from mismatched and unrelated donors, according to researchers from Dana-Farber Cancer Institute.
Potential biological factor contributing to racial disparities in prostate cancer
Researchers have uncovered a potential biological factor that may contribute to disparities in prostate cancer incidence and mortality between African-American and non-Hispanic white men in the United States, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Biomarker linked to aggressive breast cancers, poor outcomes in African-Americans
Among African-American women with breast cancer, increased levels of the protein HSET were associated with worse breast cancer outcomes, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.
Medical students find mind-body regulation training helpful
(HealthDay)—A practical approach may be used to offer mind-body regulation training to medical students, according to research published in the Fall issue of the Annals of Behavioral Science and Medical Education.
Nerve root sedimentation sign for spinal stenosis assessed
(HealthDay)—The nerve root sedimentation sign (SedSign), seen on magnetic resonance images, can differentiate lumbar spinal stenosis (LSS) from asymptomatic controls, according to a study published in the Nov. 15 issue of Spine.
Pre-op MRI of margins predicts rectal cancer outcomes
(HealthDay)—Preoperative high-resolution magnetic resonance imaging (MRI) assessment of circumferential resection margin (CRM) status predicts survival and other disease progression outcomes in patients with rectal cancer, according to a study published online Nov. 25 in the Journal of Clinical Oncology.
Experts urge US to measure, pursue our happiness
A panel of experts thinks the U.S. government should be more in touch with Americans' feelings.
Gene therapy scores big wins against blood cancers
In one of the biggest advances against leukemia and other blood cancers in many years, doctors are reporting unprecedented success by using gene therapy to transform patients' blood cells into soldiers that seek and destroy cancer.
Novel method could help bring cancer biomarkers to clinic
An international team of scientists led by Fred Hutchinson Cancer Research Center cancer proteomics expert Amanda Paulovich, M.D., has demonstrated the feasibility of large-scale, standardized protein measurements, which are necessary for validation of disease biomarkers and drug targets.
Extensive variability in olfactory receptors influences human odor perception
According to Gertrude Stein, "A rose is a rose is a rose," but new research indicates that might not be the case when it comes to the rose's scent. Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals. This substantial variation is in turn reflected by variability in how each person perceives odors.
Blunting brain tumor growth with immune activation
Researchers at the University of Calgary's Hotchkiss Brain Institute (HBI) have made a discovery that could lead to better treatment for patients suffering from brain cancer.
Flipping a gene switch reactivates fetal hemoglobin, may reverse sickle cell disease
Hematology researchers at The Children's Hospital of Philadelphia have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period. Because this fetal hemoglobin is unaffected by the genetic defect in sickle cell disease (SCD), the cell culture findings may open the door to a new therapy for the debilitating blood disorder.
Gene CUX1 discovered to play part in one per cent of all cancers
Researchers have identified a gene that drives the development of tumours in over one per cent of all cancer patients. This is the first time that the gene CUX1 has been broadly linked to cancer development.
Researchers film early concussion damage, describe brain's response to injury (w/ Video)
There is more than meets the eye following even a mild traumatic brain injury. While the brain may appear to be intact, new findings reported in Nature suggest that the brain's protective coverings may feel the brunt of the impact.
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You received this email because you subscribed to our list.
You are subscribed as pascal.alter@gmail.com
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